Both of them have been shown to be without significant effect.
But it was all without effect The two just would not fight.
I can drink a case or three of the stuff without effect.
Fire was returned by the French but without significant effect.
While the drug is effective, it's not without side effects of its own.
No form of energy production can ever be entirely without environmental effects.
He could see himself eating the food without ill effect.
All these points can be acknowledged without serious effect upon the method.
There are, however, cases in which learning can be shown to occur without good or bad effects following the behavior.
Without special effects as the main attraction, there would be no movie here at all.