As soon as the guest list became public, however, there was indeed a "major reaction."

Assuming, of course, that she didn't turn out to have a major negative religious reaction to it herself!

The Brotherhood and the government challenge each other, with both sides mindful not to push so hard as to provoke a major reaction.

The news caused a major reaction in oil markets, but the Saudis asserted that they gave no discounts.

The first major reaction came from the University of California system.

News of the criminal charges provoked major financial reactions.

One of the first major adverse reactions noted with Ofloxacin were psychiatric in nature.

That alone, he realized, in a low-tech culture, could be enough to cause a major reaction.

But no major toxic reactions were reported in the San Francisco aerosol study.

You should not expect a major reaction from investors because uncertainty is going to be with this company for a while.