The enamine will cyclize and dehydrate to give the desired quiniline (5).

The rate of this reaction is pH dependent because the protonated amine cannot cyclize.

This will oxygenate and cyclize averantin's side chain to form the ketal in averufin.

Amides may cyclize to form lactams.

Crowded triynes can cyclize to products exhibiting helical chirality.

The field of organic chem is so vast that there are literally hundreds of different ways to cyclize an "ordinary hydrocarbon."

Homocysteine can cyclize to give homocysteine thiolactone, a five-membered heterocycle.

N-terminal glutamic acid and glutamine residues can spontaneously cyclize to become pyroglutamate.

The N-acyliminium ion is a very powerful electrophile and most aromatic ring systems will cyclize under mild conditions with good yields.

However, suitably substituted stilbenes cyclize irreversibly if an aromatizing elimination or hydrogen shift process can take place.

Stilbene derivatives containing fused aromatic systems may cyclize using either of two nonequivalent ortho carbons.

In the biosynthesis of cocaine, however, only the (S)-enantiomer can cyclize to form the tropane ring system of cocaine.

Subsequently, it is proposed that a series of hydroxylations and acylations occur at C-15 and C-4 which then cyclize at these carbons.

DIBAs tend to cyclize into benzisothiazolones which do not have the same potency when used to combat retroviruses as the original compound.

If the Dps F cyclase is inactivated by mutations or gene deletions, the chain will cyclize spontaneously in random fashion.

The PKS unit is hypothesized to cyclize by a Diels-Alder-like addition similar to other natural products such as lovastatin and solanapyrone.

The discovery that tetrafluorethylene would cyclize with a wide variety of compounds to give fluorinated compounds opened up routes to a range of organofluorine compounds.

This requires appropriate diastereocontrol in the Mukaiyama aldol addition and the product silyloxycarbenium ion to preferentially cyclize, rather than undergo further aldol reaction.

The terminal Thioesterase acts solely to terminate DEBS polyketide synthesis and cyclize the macrolide ring.

After infecting a new cell this "terminal redundancy" is used by the host recombination machinery to cyclize the genome if it lacks two copies of the lox locus.

Isolated tyrocidine (Tyc) TE domains can be used to cyclize chemically derived peptidyl-thioester substrates, providing a powerful route to new cyclic compounds.

She noted the possibility that polypeptides might cyclize to form closed rings (true) and that these rings might form internal crosslinks through the cyclol reaction (also true, although rare).

Carothers surmised that the problem with the polyamides that had been made from ε-aminocaproic acid was due to cyclization reactions, so he replaced ε-aminocaproic acid with 9-aminononoic acid which would not cyclize.