The town was almost destroyed by a great fire in 1688.
In 1827 the town and the university were destroyed by fire.
In 1925, the entire town was destroyed by a fire.
In 1610, almost half the town was destroyed by fire.
A large fire destroyed almost the whole town in 1496.
In 1797, a large fire destroyed almost the entire town.
On 18 March 1560 the town was destroyed by fire.
During a civil war in 1883, the town was destroyed.
About 80% of the town was destroyed, including one hospital.
The town was destroyed by a fire in 1794, but it could not stop the town's development.
