This new class of genes has recently been shown to play a central role in malignant transformation.

Overexpression of miR-181b may play an important role in malignant transformation.

The risk of malignant transformation is similar to normal mucosa.

There have been documented cases of malignant transformation however this is rare.

Malignant transformation is the process by which cells acquire the properties of cancer.

There are many causes of primary malignant transformation, or tumorigenesis.

These activating factors are known to be important for malignant transformation and progression.

Some signs are generally associated with a higher risk of malignant transformation (see: prognosis).

However, rare malignant transformation leading to phyllodes tumors has been reported.

This form may undergo malignant transformation, although this is controversial.

Larger white patches are more likely to undergo malignant transformation than smaller lesions.

There have been a few cases reported of malignant transformation to squamous cell carcinoma.

The absence of immortalization means a cell can no longer undergo malignant transformation.

According to published results, these markers, which are highly sensitive and specific, allow to identify cells going through malignant transformation.

Accumulating evidence suggests that homeobox genes are important in malignant transformation.

Some sources claim that malignant transformation can occur, while others say this has yet to be convincingly documented.

All of these genetic abnormalities may contribute to the process of malignant transformation.

Although this type of leukoplakia may show dysplasia, the potential for malignant transformation is unknown.

Malignant transformation to squamous cell carcinoma may occur, but is unusual.

The malignant transformation rate is thought to be less than 1%, however it has been reported to be as high as 5%.

Like other germ cell tumors, germinomas can undergo malignant transformation.

High grade dysplasia represents a more advanced progression towards malignant transformation.

There is no evidence of malignant transformation.

B cells are also susceptible to malignant transformation.

The KDM4 family of proteins have been linked to malignant transformation.