During the 2010 season, Millwood went 4-16 with a 5.10 earned run average, leading the league in losses.
For the second time, he led the league in losses (20) in 1924.
Oeschger then led the league in losses during the 1918 season with 18, but still had a good earned run average of 3.03.
He won 22 games in 1916, but also led the league in losses twice.
Wells led the league in losses in 2005, going 8-18 on a Pirates team that went 67-95.
Webb finished the 2004 season with a 7-16 record, leading the league in losses.
Attempts to establish a fourth television network led to $80 million in losses last year.
The Dodgers lead the majors in one-run losses with 31.
In 1889, he led the league in losses with 34.
He led the National League in losses that year with 20.