Their data revealed that within 10 months of its discovery, the disease had become well-established.

Under the direction of the current headmaster, Tom Hamilton, the school has become well-established, steadily heading towards its 50th birthday in 2013.

By the sixteenth century, sweet oranges had become well-established and had assumed commercial importance in Europe.

Where M. cerebralis has become well-established, it has caused decline or even elimination of whole cohorts of fish.

By the mid-17th century, the industry here had become well-established.

By the early 1980s, the use of analog subcarriers for radio network distribution had become well-established.

By the end of the Palaeozoic, echinoids with club-shaped spines and beautifully regular tests had become well-established, and their distant descendants survive today.

By Aiden's death in 651, the Christian faith was becoming well-established in the area.

In the late 19th century, they had become well-established as the largest Sahrawi tribe, and were recognized as the most powerful warrior tribe of the area.

By the second half of the 1800s, the scientific study of psychology was becoming well-established in university laboratories.