ligases

Other common names for ligases include synthetases, because they are used to synthesize new molecules.

As this is a multi-step process, several different enzymes are involved, the final one being a member of the E3 family of ligases.

All four Mur ligases are topologically similar to one another, even though they display low sequence identity.

This enzyme belongs to the family of ligases, specifically those forming carbon-carbon bonds.

The tagging reaction is catalyzed by enzymes called ubiquitin ligases.

In particular, ubiquitin ligases are shown to be recruited by Numb in mammals.

Ligases can be further classified into six subclasses:

Exonucleases then remove the unpaired nucleotides, and ligases fill in the gaps.

DNA polymerases and ligases fill in the gap using the normal strand as a template.

Cullins are a family of hydrophobic proteins providing a scaffold for ubiquitin ligases (E3).

EC 6.3 includes ligases used to form carbon-nitrogen bonds (including argininosuccinate synthetase)

Ribonucleases cleave the RNA and ligases join the exons together.

Thus, presumably there exist E3 ligases (none have been identified to date) to perform the final step in Ufm1 conjugation to relevant targets.

Of particular interest are DNA ligases.

Two lipoic acid protein ligases (LplA1 and LplA2) are present in the genome.

Lipoate protein ligases proceed via an enzyme bound lipoyl adenylate intermediate.

Human genes encoding formate-tetrahydrofolate ligases include:

In general, phosphorylation is necessary for the degradation of PERs via ubiquitin ligases.

Myc-nick contains binding domains for histone acetyltransferases and for ubiquitin ligases.

Generation of a 3' poly(dA) tail can be accomplished with a variety of different ligases or polymerases.

Another group of enzymes, more specifically ubiquitin protein ligases called E3, bind to the misfolded protein.

Following the EC number classification, they belong to the group of lyases, with ligases catalysing the reverse reaction.

E3 ubiquitin ligases have various roles in the ubiquitin pathway for immune signaling, which include plant defenses.

Ligases are classified as EC 6 in the EC number classification of enzymes.

The biochemistry of Polony sequencing mainly relies on the discriminatory capacities of ligases and polymerases.