Price led Oklahoma with 26 points, including 18 in the second half.
Colorado led Oklahoma by 19-6 at halftime.
Capel led Oklahoma to a 13-18 record in the 2009-2010 season, the first losing season at Oklahoma since 1981.
Like Vick last year, Heupel is being discovered late in the season after leading Oklahoma to a surprising 6-0 start.
He also led Oklahoma to the Big 12 championship.
Despite leading Oklahoma to an 11-2 record and a No. 6 national ranking as a junior, his play at quarterback was regularly criticized.
Collins returned on the next possession and led Oklahoma to a touchdown in 11 plays, but didn't play after that.
He missed two games his senior season but still led Oklahoma in sacks with 11.
Switzer led Oklahoma to three national titles and 157 victories in 16 seasons, an outstanding record.
Sooners quarterback Sam Bradford's three touchdowns lead Oklahoma to the win.
