It is probable that this signal is restricted to the vicinity of activated spines and is amplified by release from intracellular stores.

Calcium contained within intracellular stores is released to the cytosol when InsP 3 binds to its receptor (Fig. 2c ).

This molecule acts in calcium signaling by releasing calcium from intracellular stores.

In mononuclear leukocytes: Cell proliferation, calcium release from intracellular stores and decreased TNF production.

Ultimately, these two messengers result in a release of calcium from intracellular stores and a subsequent flux of extracellular calcium into the cytoplasmic space.

However, the other opportunity such as Na-Ca exchange as well as small contribution from intracellular stores need to be explored.

In these cells, cAMP-dependent phosphorylation decreases Ca 2+release from intracellular stores and slows the frequency of Ca 2+oscillations.

Glaucine has no effect on intracellular calcium stores, but rather, does not allow the entry of Ca after intracellular stores have been depleted.

Vasopressin also increases the concentration of calcium in the collecting duct cells, by episodic release from intracellular stores.

Glutamate activation of ionotropic receptors leads to a rapid excitatory signal based on cation influx that can cause release of calcium from intracellular stores.