tissue factor

The best known function of tissue factor is its role in blood coagulation.

Tissue factor is not needed to activate the intrinsic pathway.

The main mechanism is exposure of tissue factor to the blood coagulation system.

Although sometimes used as a synonym for tissue factor, this is a misconception.

Tissue factor, which is found on most cells outside the blood system, also exerts powerful regulatory effects throughout the body.

And tissue factor may lead to new life-saving treatments for accident victims.

They are also activated by thrombin (formed with the help of tissue factor).

Tissue factor is found on the outside of blood vessels - normally not exposed to the bloodstream.

However, partial thromboplastin is just phospholipids, and not tissue factor.

Scientists hope to develop techniques using tissue factor to test theories about why some people are predisposed to heart disease.

The test is termed "partial" due to the absence of tissue factor from the reaction mixture.

They continued looking for tissue factor.

As blood flows, tissue factor forms clots that pave the way for the severe bleeding.

This is due to the differences between different batches of manufacturer's tissue factor used in the reagent to perform the test.

Many trauma patients suffer from an overwhelming activation of tissue factor and thus massive hyperfibrinolysis.

Tissue factor (TF) is also known to be present at increased levels around malignant cells.

Currently, recombinant tissue factor is available and used in some PT assays.

Various mechanisms, such as deficiency of protein S and tissue factor pathway inhibitor, are said to be responsible.

Normal coagulation is initiated by the release of tissue factor from damaged tissue.

Now scientists have used genetic engineering techniques to create bacteria that produce the tissue factor molecule and factor 7.

White blood cells known as macrophages seem central to the process by releasing a protein called tissue factor on the surface of the cells.

"Tissue factor," she demanded, and the nurse slipped a hypo into Crusher's palm.

Factor X has been shown to interact with Tissue factor pathway inhibitor.

Phospholipid is available as an independent reagent or in combination with tissue factor as thromboplastin.

The beginning of the process is thought to be initiated by tissue factor effected thrombin production, which leads to fibrin deposition.