It was rerouted by the following year to follow its current alignment between Ashford and Machias.

M-21 would be rerouted to follow Interstate 196 through Grand Rapids in 1964 .

In the early 1940s, NY 32 was rerouted to follow a new highway east of the hamlet.

Construction on the highway began in the mid-1950s and was completed by 1958, at which time US 4 was rerouted to follow the riverside roadway.

NY 16 was rerouted to follow the new highway for two miles (3 km) before exiting the freeway and returning to its previous alignment.

I-95 was rerouted to follow Route 128 around Boston.

During the same time period, NY 37 was rerouted to follow a new bypass around the southern edge of Ogdensburg.

NY 252 was rerouted in the late 1950s to follow a new, more southerly alignment through Chili.

In 1962 and 1963, the state transferred the highway to county control when US 2 was rerouted to follow the completed I-75 freeway.

US 31 was rerouted to follow what is now the I-196 freeway in 1963.