Wigand claimed that B&W had introduced chemicals such as ammonia into cigarettes to increase nicotine delivery and increase addiction.

Levulinic acid is used in cigarettes to increase nicotine delivery in smoke and binding of nicotine to neural receptors.

If nicotine delivery is the sole or primary purpose for smoking, then "why was Premier such a failure?"

This design produces a smoke-like vapour that can be inhaled and provides a vehicle for nicotine delivery into the bloodstream via the lungs.

In another internal document, a Philip Morris research supervisor gave the game away in a 1972 memorandum by acknowledging the true purpose of a cigarette: nicotine delivery.

Other research documents also looked at the issue of "optimal" nicotine delivery.

One 1990 Philip Morris research memorandum, for example, states, "We have shown that there are optimal nicotine deliveries for producing the most favorable physiological and behavioral responses."

The addition of glass to dipping tobacco would not be beneficial for increasing nicotine delivery, as bleeding and inflammation would be likely to reduce the uptake of nicotine.

If the F.D.A. forces manufacturers to reduce the nicotine delivery of cigarettes, will people ingest less nicotine?

"Project Ariel is dormant after the first samples give a tremendous kick, even though the nicotine delivery is small," the research chronology stated.