For example, it plays an important role in the brain's response to neuronal injury.

The oligonucleotide microarray screen indicates that hundreds of genes are regulated by neuronal injury, and that this technique is a powerful primary screen for such changes.

Con-G reduces the strength of excitotoxic intracellular Ca actions and blocks different neuronal injuries in vitro.

Acute neuroinflammation is generally caused by some neuronal injury after which microglia migrate to the injured site engulfing dead cells and debris.

A major cause of neuronal injury is release of the excitatory neurotransmitter glutamate.

This usually leads to an excessive activation of glutamate receptors, which may lead to neuronal injury.

Given the associated risks, it would be foolish to administer / express Mutant as a preventive measure from neuronal injury.

Studies have shown that in cases of reversible neuronal injury, such as axotomy, neuron signals cause microglia to produce trophic factors, which promote neuron survival.

As a pharmaceutical agent, some research has suggested that administration of dehydroascorbic acid may confer protection from neuronal injury following an ischemic stroke.

These three microglia mediators are currently thought to participate in neuronal and glial injury in vivo [ 10 45 ] .