The enzymatic activity can also be located on an enzyme associated with the intracellular domain.
Therefore, the opposing functions these receptors have must be attributed to differences in their intracellular domains.
In fact, these intracellular domains determine the opposite functions of activation and inhibitory receptors.
Finally, we assume that there is a complete isolation of the intracellular domain and the surrounding tissue.
Some also contain an intracellular domain like shown in the image.
Its activation appears to involve an intracellular domain.
The editing site is found within the second intracellular domain.
CD36 is modified with 4 palmitoyl chains, 2 on each of the two intracellular domains.
CD28 possesses an intracellular domain with several residues that are critical for its effective signalling.
The loops connecting the alpha helices form extracellular and intracellular domains.
