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March haemoglobinuria is usually not life threatening.
Haemaglobinuria in the morning is suggestive of paroxysmal nocturnal haemoglobinuria.
A rare condition, paroxysmal nocturnal haemoglobinuria, results in red cells which lack CD59.
It is possible to use an ammonia sulphate precipitation test in order to distinguish between haemoglobinuria and myoglobinuria.
It should not be confused with the Dressler's syndrome of haemoglobinuria named for Lucas Dressler, who characterized it in 1854.
In animals, babesiosis is suspected by observation of clinical signs (haemoglobinuria and anaemia) in animals in endemic areas.
Although it has no neurotoxic effect, it produces a lethal haemolytic effect, and may reduce haemoglobin levels by as much as 75%, leading to haemoglobinuria.
In medicine, hemoglobinuria or haemoglobinuria is a condition in which the oxygen transport protein hemoglobin is found in abnormally high concentrations in the urine.
The Dutch physician Enneking coined the term "paroxysmal nocturnal hemoglobinuria" (or haemoglobinuria paroxysmalis nocturna in Latin) in 1928.
Common sequelae include haemoglobinuria "red-water", disseminated intravascular coaguation and "cerebral babesiosis" caused by sludging of erythrocytes in cerebral capillaries.
In addition to dietary insufficiency, malabsorption, chronic blood loss, diversion of iron to fetal erythropoiesis during pregnancy, intravascular haemolysis and haemoglobinuria or other forms of chronic blood loss should all be considered.
The first signs of exposure, which can take several hours to become apparent, are headaches, vertigo and nausea, followed by the symptoms of haemolytic anaemia (high levels of unconjugated bilirubin), haemoglobinuria and nephropathy.
A urine test strip showing positive for blood can also indicate haemoglobinuria, which is not detectable using a microscope due to the lysis of red blood cells in the urinary tract (particularly in alkaline or dilute urine), or intravascular haemolysis.
It has been referred to as "epidemic hemoglobinuria of the newborn".
This is a different process than march hemoglobinuria.
Individuals with hemoglobinuria may exhibit dark-colored or bloody urine.
Some forms are self-inflicted (march hemoglobinuria), if not intentionally, through repeated mechanical motions.
All of these, except paroxysmal nocturnal hemoglobinuria, are hereditary genetic disorders.
The symptoms are fever and chills, sometimes with back pain and pink or red urine (hemoglobinuria).
This may result in hemoglobinuria.
Occasionally "hemoglobinuria" is used synonymously, although more precisely it refers only to hemoglobin in the urine.
Flatmark T. Studies on the hemolytic mechanism in March hemoglobinuria.
Hemoglobinanemia, methemalbuminemia, hemoglobinuria and hemosiderinuria (where there is significant intravascular hemolysis).
Infected individuals suffer from hemoglobinuria followed by jaundice, a persistently high fever, chills, and sweats.
Exertional hemoglobinuria (or exercise hematuria) may refer to:
Paroxysmal nocturnal hemoglobinuria.
Paroxysmal hemoglobinuria can refer to:
However, athletic nephritis may be secondary to the hemoglobin load on the kidneys caused by the hemolysis in march hemoglobinuria.
Paroxysmal nocturnal hemoglobinuria (rare acquired clonal disorder of red blood cell surface proteins)
Paroxysmal nocturnal hemoglobinuria; the mechanism of hemolysis and its relation to the coagulation mechanism.
Hemosiderin in the kidneys have been associated with marked hemolysis and a rare blood disorder called paroxysmal nocturnal hemoglobinuria.
Paroxysmal cold hemoglobinuria (rare)
Diuresis induced by an infusion of normal saline until the intense red color of hemoglobinuria ceases is usually adequate treatment.
An uncommon blood disease called paroxysmal nocturnal hemoglobinuria can cause blood clots in the liver, the spleen or beneath the skin.
Defects of 'GPI anchors' occur in the rare disease paroxysmal nocturnal hemoglobinuria.
Splenomegaly, severe headache, hepatomegaly (enlarged liver), hypoglycemia, and hemoglobinuria with renal failure may occur.
In some cases, aplastic anemia is associated with another blood disorder called paroxysmal nocturnal hemoglobinuria (PNH).
Castle and his team later characterized the red blood cell defects that are responsible for paroxysmal nocturnal hemoglobinuria and hereditary spherocytosis.