Counter reformation actions of the Emperor's army against the Kuruts in the 17th century had a grave effect on the town's life.

This led to battle between the French and the Utina, which had grave effects for both sides.

Such changes could result in the gravest effects of climate change through sudden human migration.

At least one major economist has proposed that the fear of youth can have grave effects on the economic health of nations.

Problems with disciplining doctors have captured the attention of state and federal lawmakers in recent months following a detailed study of medical error and its grave effects.

Expedited approval of new prescription drugs can save lives, but increases the risk of belated discovery of grave side effects.

Biologists say these extinctions will have grave effects.

Another such scene as this morning's may have very grave effects.

So do i. What I accomplish here will have grave effects on our nation's policy toward the United States.

Further changes to the docks were proposed, and the town authorities realised the potential grave effect on public health, particular in the riverside St Thomas area.