He was an efficient, outspoken and extremely irritable Australian.

John is extremely irritable and refuses to sell them to the offer of $75.

Have severe mood changes, from being extremely irritable to overly silly or happy.

She is extremely irritable,grouchy,and impatient; hence her name Fastidious.

Some patients, unaware that they are depressed, instead admit to feeling extremely irritable, angry or hostile.

The team was extremely irritable now that they'd left land behind.

Being extremely irritable, he is very cantankerous in his dealings with the other passengers.

The euphoria was gone and in its place I felt extremely irritable.

He was tempera mental, volatile, and extremely irritable with me.

He looked extremely irritable, likely to explode at any moment.