Much of the ion transport taking place in the distal convoluted tubule is regulated by the endocrine system.

This hypotonic filtrate is passed to the distal convoluted tubule in the renal cortex.

The cortical thick ascending limb drains urine into the distal convoluted tubule.

Atrial natriuretic peptide causes the distal convoluted tubule to excrete more sodium.

Since Ca is actively reabsorbed in the distal convoluted tubule, loop diuretics do not generally cause hypocalcemia.

Use of carbenicillin can cause hypokalemia by promoting potassium loss at the distal convoluted tubule of the kidney.

In the distal convoluted tubule sodium is transported against an electrochemical gradient by sodium-chloride symporters.

It reduces blood volume by acting on the kidneys to reduce sodium (Na) reabsorption in the distal convoluted tubule.

It is adjacent to the distal convoluted tubule, the most distal segment of the renal tubule.

The cells of the macula densa are sensitive to the concentration of sodium chloride in the distal convoluted tubule.

The distal convoluted tubule has a different structure and function to that of the proximal convoluted tubule.

In the presence of parathyroid hormone, the distal convoluted tubule reabsorbs more calcium and excretes more phosphate.

By impairing Na transport in the distal convoluted tubule, hydrochlorothiazide induces a natriuresis and concomitant water loss.

Like the structurally related thiazide diuretics, xipamide acts on the kidneys to reduce sodium reabsorption in the distal convoluted tubule.

Aldosterone further increases the Na and HO reabsorption in the distal convoluted tubule of the nephron.

The straight or collecting tubes commence in the radiate part of the renal cortex, where they receive the curved ends of the distal convoluted tubules.

Inorganic fluoride inhibits adenylate cyclase activity required for antidiuretic hormone effect on the distal convoluted tubule of the kidney.

Each distal convoluted tubule delivers its filtrate to a system of collecting ducts, the first segment of which is the connecting tubule.

In the proximal and distal convoluted tubules non-ionised acids and weak bases are reabsorbed both actively and passively.

PTH effect is mediated through phosphorylation of regulatory proteins and enhancing the synthesis of all transporters within the distal convoluted tubule.

Bendroflumethiazide is a thiazide diuretic which works by inhibiting sodium absorption at the beginning of the distal convoluted tubule (DCT).

Mercurial diuretics cause diuresis by reducing the reabsorption sodium in the ascending loop of Henle, thus causing more water being delivered to the distal convoluted tubule.

Distal convoluted tubule: Once leaving the loop of Henle the thick ascending limb can optionally reabsorb and re increase the concentration in the nephrons.

Aldosterone regulates the body's concentration of electrolytes, primarily sodium and potassium, by acting on the distal convoluted tubule of kidney nephrons to:

Specifically, the LGR5+ve stem cells contribute into the formation of the thick ascending limb of Henle's loop and the distal convoluted tubule.