For James, it represents the biggest challenge of his career.

He reveals: 'It is the ultimate challenge of my career.

I think this is the greatest challenge of his career.

To come up against Tiger would probably be the biggest challenge of my career.

But this will be the largest challenge of his career.

She felt ready to face the greatest challenge of her diplomatic career.

It occurred to me that if he were, then he might present the greatest challenge of my career as a Brother.

But analysts warn that he faces the challenge of his career.

It was apt to be the most significant challenge of his career as an Incarnation.

As for now, he is succeeding in this latest challenge of his career.