Now, overnight, it became the central cause of the stock market collapse.

The wage issue soon became the central cause.

Her central cause is defending the rights of women and children.

"Yet that is a central cause of the Abbot's quarrel."

Crack was a central cause of crime in the 1980's.

Such an approach requires that "causes be ranked hierarchically" so as to identify a single, central cause.

The central cause for concern was the 20-page section devoted to advice on sexual matters.

Generally the ego is the central cause of all mental conflict.

The public register was a fundamental and central cause for concern to us Greens.

The increase of urbanization around the world is considered by some a central cause.