It has been proposed that polymorphisms in these enzymes are associated with DNA damage and subsequently the individual's risk of cancer susceptibility.
There are genes modifying the cancer susceptibility of these mouse models.
C1orf38 has been associated with cancer susceptibility.
However, shortened telomeres impair immune function that might also increase cancer susceptibility.
MBD4 mutant mice develop normally and do not show increased cancer susceptibility or reduced survival.
In some types of cancer susceptibility, such as lung cancer, an excess of cancers in relatives can be seen.
This genetic testing algorithm depicts the multistep process of testing for cancer susceptibility.
Explanation of how inheritance of genetic factors may affect cancer susceptibility.
Such information may ultimately help determine individual cancer susceptibilities.
Genetic information may also provide a direct health benefit by demonstrating the lack of an inherited cancer susceptibility.