Forbes-Albright syndrome, which refers to galactorrhoea-amenorrhoea associated with a pituitary tumour.

However, an album planned for November 2006 was delayed due to the removal of a benign pituitary tumour.

In fact since the mid-1990s he had been suffering from a medical condition - a benign pituitary tumour - wrongly diagnosed as depression.

On 24 October 2007, it was discovered that there had been a regrowth of his pituitary tumour and bleeding into his brain.

Watson has been reported as saying: "It [his first pituitary tumour] changed my priorities.

This secondary hyperprolactinaemia usually indicates the presence of a large pituitary tumour not secreting prolactin or a cyst.

Inhibition of miR-26b expression alongside upregulation of miR-128 suppresses the colony-forming ability and invasiveness of pituitary tumour cells.

In addition to assessing the size of the pituitary tumour, doctors also look for damage to surrounding tissues, and perform tests to assess whether production of other pituitary hormones is normal.

A pituitary tumour which had caused him to go blind since 1951 (its growth placing pressure on the optic nerve), ended his artistic career, though he continued writing until his death in 1957.

The regulation of PTEN by miR-26b sees direct effects of miR-26b on pituitary cell tumour behaviour, with miR-26b inhibition suppressing pituitary tumour growth in xenografts.

Starting in 2010, Kösen received Gamma Knife treatment for his pituitary tumour at the University of Virginia Medical School and has also been provided with medication to control his excessive levels of growth hormone.

One important variety of bilateral scotoma may occur when a pituitary tumour begins to compress the optic chiasm (as distinct from a single optic nerve) and produces a bitemporal paracentral scotoma, and later, when the tumor enlarges, the scotomas extend out to the periphery to cause the characteristic bitemporal hemianopsia.