A low therapeutic index indicates that there is a high risk of toxicity when using the drug.

Medication is said to have a narrow or wide therapeutic index.

A quantitative measure of this fact is called the therapeutic index.

It has a favorable therapeutic index of 28.1 in mice.

However this use has been limited due to their narrow therapeutic index, and the development of more-advanced medicines for these conditions.

Tobramycin is thus said to be a drug with a narrow therapeutic index.

The result showed a favorable safety profile for the drug with a therapeutic index in rats greater than 250.

It also showed a higher therapeutic index, yet the cardiotoxicity remained.

Patients treated often suffered side effects due to the narrow therapeutic index of these products.

In addition, the therapeutic index of dextroproxyphene is relatively small.