"And the earliest events that start tumorigenesis are the most fundamental."

BP1 expression might therefore be involved in tumorigenesis in mice.

It may play a role in regulation of cell cycle progression and tumorigenesis.

There are many causes of primary malignant transformation, or tumorigenesis.

This technique has been used to follow tumorigenesis and response of tumors to treatment in animal models.

Granulin family members are important in normal development, wound healing, and tumorigenesis.

However, it is not known whether this production is a contributing cause or an effect of tumorigenesis.

Oct-4 has been implicated in tumorigenesis of adult germ cells.

Protein-protein interaction networks provide valuable information on tumorigenesis in humans.

"And we're actively pursuing ways to detect those mutations in the early stage of tumorigenesis."

The methylation state of some genes can be used as a biomarker for tumorigenesis.

This may provide another possible route for tumorigenesis via the Hedgehog pathway.

Their study, although greatly increasing our understanding of tumorigenesis, has provided little information about normal haemopoietic mechanisms.

This expression has important implications for the study of tumorigenesis and lethal recessive genes.

The early genetic events in tumorigenesis are difficult to measure clinically, but can be simulated according to known biology.

All this supports the conclusion that increase in tumorigenesis is associated with defects other than aneuploidy alone.

Defects in this segregation can cause genetic instability, a condition which is highly associated with tumorigenesis.

Notably the mutant mice also showed increases in tumorigenesis.

As one would expect, Skp2 overexpression promotes growth and tumorigenesis in a xenograft tumor model.

Ultimately, the tumorigenesis of schwannomas is not solely dependent on one gene locus alone.

Rereplication has been implicated in tumorigenesis in model organisms and humans.

Whether aneuploidy alone is a sufficient driving cause during tumorigenesis or rather a mere consequence has been a matter of scientific debate.

There was a correlation between BP1 expression and tumorigenesis in mice (Table 1).

Exposure to aristolochic acid is associated with a high incidence of uroepithelial tumorigenesis.

MUC16 has been shown to play a role in advancing tumorigenesis and tumor proliferation by several different mechanisms.