It took a heavy toll on his physical health and often brought him close to death.

The first half had taken a heavy toll on both teams.

Unfortunately situation has taken a heavy toll on the project.

Our country's economic challenges continue to take a heavy toll, particularly on those without work.

People are also taking a heavy toll, the visitors say.

The social impact is enormous and takes a heavy toll.

But 30 years of neglect had taken a heavy toll.

The strain of work during the war took a heavy toll on his health.

However, a series of strokes in the late 1990s and early 2000s took a heavy toll on him.

The answer turns out to be: The losses do indeed take a heavy toll.

Now the disease has taken a heavy toll among those trained adults of working age.

That would take a heavy toll on National, 42 percent of whose sales are to the auto industry.

Despite that good news, six years of preparations have taken a heavy toll on Atlanta.

But insect and human threats are taking a heavy toll on them.

These have taken a heavy toll on the Gaza civilian population.

However, the effort took a heavy toll on his health, from which he never entirely recovered.

Feeding more than six billion human bodies takes a heavy toll on the Earth's resources.

Old resentments, as always, took a heavy toll on the government.

The war took a heavy toll, especially in the northern British colonies.

The occupation took a heavy toll, particularly on the city's cultural heritage.

Like most wars, this one took a heavy toll on the inhabitants.

The road to Kentucky always takes a heavy toll, and this year is no exception.

The endless brutality took a heavy toll on the community.

This took a heavy toll on him financially and emotionally.

Clearly, price increases because of the weak dollar have taken a heavy toll.