In Texas male hispid cotton rats also had larger home ranges than females.

Hispid cotton rats have been noted as one of the most prolific mammals in the Southeast.

The mean hispid cotton rat population density range for all studies was 5.3 to 31.1 rats per hectare.

Sand pine scrub has little ground cover and is marginal habitat for hispid cotton rats.

Some studies have suggested that hispid cotton rats are mainly nocturnal, but activity has been observed at all hours.

Mammalian predators did not have a substantial effect on hispid cotton rat population density.

Gestation in hispid cotton rats lasts approximately 27 days.

Male hispid cotton rats exhibit a lower degree of habitat selectivity than females.

Hispid cotton rats occur in grassy areas or early-successional habitats within open woods.

In Georgia, a density of 15 hispid cotton rats per acre was considered the predator-limited carrying capacity.

Habitat use and preference by hispid cotton rats usually appears to depend on the density of monocots.

For example, hispid cotton rats may respond favorably to a high percentage of dicots in a stand if cover remains optimal.

Cameron and McClure compiled reports of hispid cotton rat population densities.

Hispid cotton rats are active year-round.

Populations in the northern part of hispid cotton rat range experience dramatic declines in the nonbreeding season.

Hispid cotton rats occupy a wide variety of habitats within their range but are not randomly distributed among microhabitats.

In Georgia, hispid cotton rat spring abundance in old fields was lowest following drought and extreme winter cold.

Hispid cotton rats are omnivorous, but the major portion of their diet consists of green vegetation.

There are many small animals like fox squirrels, hispid cotton rats, soft-shelled turtles etc. to numerous to mention.

In Florida, sand pine (P. clausa) scrub has been invaded by hispid cotton rats for short periods.

In Kansas, most hispid cotton rat mortality was associated with severe weather in March and April.

The reductions in hispid cotton rat populations were associated with sharp declines in vegetative biomass and cover.

Hispid cotton rats are preyed on by many birds and reptiles, and by other mammals.

Hispid cotton rats occur in mesquite (Prosopis spp.)

The rising water tables favor marsh rice rats (Oryzomys palustris) over hispid cotton rats.

Molecular systematics and phylogeography of the Sigmodon hispidus species group.

S. sigmodontis - cotton rat (Sigmodon hispidus)

It has been recorded in the hispid cotton rat (Sigmodon hispidus) in Florida and Texas.

It primarily infects the hispid cotton rat (Sigmodon hispidus), but has also been found in the marsh rice rat (Oryzomys palustris).

Koprowski developed the polio vaccine by attenuating the virus in brain cells of the cotton rat (Sigmodon hispidus), a New World species susceptible to polio.

Listrophorus klebergi - hispid pocket mouse (Chaetodipus hispidus); hispid cotton rat (Sigmodon hispidus)

The hispid cotton rat (Sigmodon hispidus) is a rodent species long thought to occur in parts of South America, Central America, and southern North America.

In the south, the hispid cotton rat (Sigmodon hispidus) and the rice rat regularly occur together; water levels are known to influence relative abundance of these two species in Florida.

Polygenis gwyni is a flea that commonly infects the hispid cotton rat (Sigmodon hispidus) in the southern United States; it is also frequently found on other species ecologically associated with the cotton rat.

Undescribed or unidentified species have been found on the hispid cotton rat (Sigmodon hispidus) in the southern United States, the marsh rice rat (Oryzomys palustris) in Florida, and Leontopithecus rosalia, Physalaemus soaresi, Cacajao calvus, and Lagothrix lagotricha in Brazil.