Some alleles result in more severe degrees of enzyme inefficiency.

The histories revealed in each a severe degree of sexual inhibition.

No troops could have stood better; and the fire of both artillery and musketry has been described as to the last degree severe.

But once hit, it began to list a severe 20 degrees, a sign it would sink.

Stages 2 and 3 represent progressively more severe degrees of virilization.

As I still pursued my journey to the northward, the snows thickened and the cold increased in a degree almost too severe to support.

More concerning are the moderate to severe degrees of breast engorgement.

A large proportion of individuals with Down syndrome have a severe degree of intellectual disability.

Depression incapacitates to a certain degree, maybe a very severe degree.

The bad example given by public administration is unacceptable, as is happening to a particularly severe degree in Portugal.