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"In a genetic defect, some people lack the repair enzyme.
But picking apart the molecular basis of the repair enzymes in humans proved exceedingly difficult.
But the DNA repair enzymes greatly speed up the process.
By comparing several strands, repair machines will dramatically improve on nature's repair enzymes.
Overwhelmed repair enzymes clung desperately to shredded genes and barely delayed the inevitable.
People may differ in their ability to produce repair enzymes, she said, "which might underlie what we see in different tanning abilities."
But we believed nanomachines could repair it all, and much more efficiently than her body's natural repair enzymes could ever hope to.
During an organism's lifetime, the lost information is mostly restored by a suite of DNA repair enzymes.
Repair enzymes compensate somewhat by detecting and repairing certain kinds of damage to DNA.
CPDs are readily repaired by nucleotide excision repair enzymes.
Sevanian made major contributions to the understanding of phospholipases as repair enzymes for oxidized membrane lipids.
Alternatively it may be recombined into the cell's genome by its DNA repair enzymes.
The uracil bases are removed by the repair enzyme, uracil-DNA glycosylase.
The fragments seem to have stimulated DNA repair enzymes, which in turn led to melanin production throughout the epidermis, she said.
This enzyme is the major repair enzyme involved in the defense against accumulation of the 8-OH-dG adducts discussed above.
The genome encodes DNA repair enzymes homologous to those in both bacteria and eukaryotes.
This approach was used to identify novel inhibitors of proteasome-mediated protein degradation and DNA repair enzymes.
It is probably no accident that nearly all of the so-called "accelerated aging diseases" are due to defective DNA repair enzymes.
Once damage is sensed, the checkpoint delays the cell cycle to allow DNA repair enzymes sufficient time to execute their activities.
Evidence also shows that checkpoint proteins interface with DNA repair enzymes [ 4 ] .
Protective effect of rutin, a flavonol glycoside, on the carcinogen-induced DNA damage and repair enzymes in rats.
The few that survived had developed enzymes which verified the genetic material and broke up thymine dimer bonds, known as excision repair enzymes.
The DNA repair enzymes then replace the cells DNA with that of the chimeraplast.
Pyrimidine dimers introduce local conformational changes in the DNA structure, which allow recognition of the lesion by repair enzymes.
Xeroderma patients, by contrast, often lack both the short- and the long-term repair enzymes, and hence can suffer both immediate cell death and slower acting tumors.