The gene for growth hormone has been isolated and the controlling promoter region identified.
The polymorphism occurs in the promoter region of the gene.
Over 200 potential transcription factor binding sites have been identified within the promoter region.
A promoter region is located before the -35 and -10 Consensus sequences.
A distinctive feature of the gene is that it begins with two promoter regions.
Though these two regulatory elements work against each other, both sequence types affect the promoter region in very similar ways.
There is a common polymorphism known as 4G/5G in the promoter region.
Polymorphisms have been described for this gene and its promoter region.
Its promoter region is classically used to demonstrate Notch1 signaling.
The binding sites are not evenly distributed within promoter region.
