Median survival time was the primary endpoint in the survival arm.

The primary endpoint was the rate of change in lung function over one year on treatment.

Despite not meeting the primary endpoint, notable treatment effects were seen in certain subgroups.

Since tolevamer did not reach its primary endpoint in this study, the development was halted.

The primary endpoint was prostate cancer incidence as determined by routine clinical management.

However, if the primary endpoint for efficacy is the need for donor blood, differences become apparent.

Prevention studies with all-cause mortality as the primary endpoint usually follow this design.

The primary endpoint in the trial was to show a difference in the number of patients with disease progression at 6 months.

On July 27, 2009 the company announced that the drug had failed to meet its primary endpoint in this trial.

What the primary endpoint will be is decided before the study begins.