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The animals also developed a second hallmark of Alzheimer's disease - neurofibrillary tangles.
Neurofibrillary tangles are twisted structures formed from part of the nerve.
Alzheimer's disease is characterized by plaque and neurofibrillary tangles in the brain.
Other conditions in which neurofibrillary tangles are commonly observed include:
The brain regions affected contain neurofibrillary tangles, similar to those seen in Alzheimer's disease.
Eventually, they form neurofibrillary tangles inside nerve cell bodies.
Furthermore, this silencing showed a dramatic reduction in the number of neurofibrillary tangles.
On examining her brain, he found senile plaques and neurofibrillary tangles.
Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer's disease.
The unbound tau clumps together in formations called neurofibrillary tangles.
This experiment resulted in the formation of neurofibrillary tangles and pretangle formations.
Pathologic page about Neurofibrillary tangles, by the University of Oklahoma.
Dock3 has been shown to undergo redistribution and association with neurofibrillary tangles in brain samples from Alzheimers patients.
Instead, it shifts it to neurofibrillary tangles, the other abnormal structure found in the brains of Alzheimer patients.
Hyperphosphorylation of tau protein can also result in the formation of neurofibrillary tangles.
One of the important differences between normal aging and pathological aging is the location of neurofibrillary tangles.
Neurofibrillary tangles and senile plaques, characteristic of Alzheimer's disease, are not common unless the person is demented.
With two Italian physicians, he used the staining techniques to identify amyloid plaques and neurofibrillary tangles.
Looking at other samples of hypothalamus, spinal cord, and cortex, all were full of neurofibrillary tangles.
However, large numbers of senile plaques and neurofibrillary tangles are characteristic features of Alzheimer's disease.
"Neurofibrillary tangles" (twisted fragments of protein within nerve cells that clog up the cell)
The most common is Alzheimer's, which is characterized by neurofibrillary tangles - misshaped proteins - and plaques.
AD is characterized by the destruction of specific cortical nerve cells, neuritic plaques, and neurofibrillary tangles.
Neurofibrillary Tangles - a definition (Flash video)
Both amyloid plaques and neurofibrillary tangles are clearly visible by microscopy in AD brains.
Słownik medyczny