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In this way, cyclin D acts as a mitogenic signal sensor.
Interestingly, this synergy is only observed in response to mitogenic stimulation by Ras.
It is not a strong mutagen, but acts as a promoter through mitogenic effects on gene expression.
Many differentiated cells retain the ability to return to the cell cycle when confronted with the appropriate mitogenic stimulus.
This suggests that Dimefox has mitogenic activity.
Moreover, Sap1a-mediated transcription is activated by mitogenic signals but not by cell stress.
A strong mitogenic stimulation was employed in order to obtain the maximum cytokine-secreting potential of the effector population.
Proto-oncogenes are often involved in signal transduction and execution of mitogenic signals, usually through their protein products.
It has growth-regulating, insulin-like and mitogenic activities.
This synergism is only observed in response to activation of mitogenic signaling pathways by Ras.
This might be due to a slight mitogenic response to low levels of CEES.
The mitogenic effect is temporary and does not appear to change follicular structure, leading to indefinite minoxidil application to maintain growth.
They contain no functional p53, a potent tumor suppressor gene, and so are highly sensitive to mitogenic stimuli.
Apart from their mitogenic activity, SAgs are able to cause symptoms that are characteristic of infection.
Tetrachlorodecaoxide is also mitogenic and chemotactic.
This leads to morphological changes, abnormal mitogenic signals and sustained activity can result in apoptosis of the host cell.
This could be accomplished by finding the correct ratio of mitogenic signals like ERK to p38.
By contrast, the same M1 receptor was mitogenic in CHO cells.
Down regulation of the cyclin-dependent kinase inhibitor p21 gene by Dimfox may be connected to the observed mitogenic activity.
Mitogenic effect of PIP was observed on both normal and malignant breast epithelial cells.
VEGF is a dimeric glycoprotein and has specific mitogenic activity for endothelial cells.
The vasoconstrictor and mitogenic peptide endothelin-1 (ET-1) is believed to play a part in fibrosis and collagen production.
A putative growth factor expressed in the respiratory epithelium is endothelin-1 (ET-1), a vasoconstrictor and mitogenic peptide.
FAK is phosphorylated in response to integrin engagement, growth factor stimulation, and the action of mitogenic neuropeptides.