The ester group is slowly hydrolyzed by metabolic enzymes, releasing steady doses of the active ingredient.
In addition, some of these metabolic enzymes are inducible and have polymorphic variation.
The structure is named after triosephosphate isomerase, a conserved metabolic enzyme.
In addition to controlling metabolism at the transcriptional level, sirtuins also directly control the activity of metabolic enzymes.
Shared metabolic enzymes can cause drugs to remain in the bloodstream much longer in higher concentrations than if individually taken.
Furthermore the metabolic enzymes of bacteria used in the Ames test differ substantially from those in mammals.
In the absence of some key metabolic enzymes, the products of intermediary metabolism accumulate.
The hepatoprotective action of andrographolide is related to activity of certain metabolic enzymes.
It is a metabolic enzyme involved in the pentose phosphate pathway.
Using these methods, researchers were able to identify over 2,000 metabolic enzymes obtained by various eukaryotic parasites from lateral gene transfer.
