luteinization

It is when an area of luteinization occurs along with stromal hyperplasia.

The surge also initiates luteinization of thecal and granulosa cells.

Patients who are pregnant sustain the ovarian luteinization process through the production of hCG.

Third, FS is strongly expressed during luteinization, but is undetectable at luteolysis.

Therefore, the loss of oocyte BMP-6 and -15 at ovulation undoubtedly plays an especially prominent role in activating luteinization.

This type of tumor derives from a previous folliculoma or thecoma that luteinization has endured, acquiring the ability to produce and to accumulate the hormone.

As hCG causes the ovary to undergo extensive luteinization, large amounts of estrogens, progesterone, and local cytokines are released.

In CL, moderate amounts of BMPR-IA mRNA were expressed as it underwent luteinization and luteolysis.

In the CL-I, BMP-3b mRNA was expressed at low to moderate levels in the TLC and TE cells during luteinization (Fig.

Second, the fact that CL BMP-2 expression is suppressed and activated during luteinization and luteolysis, respectively, suggests that BMP-2 might be a novel luteinization inhibitor.

And fourth, a role of BMPR-IB in luteogenesis was suggested by our finding that luteinization and luteolysis, respectively are characterized by the absence and presence of BMPR-IB expression in the CL.

The general principle to emerge from our data is that the developmental programs of folliculogenesis (recruitment, selection, and atresia), ovulation and luteogenesis (luteinization and luteolysis) are accompanied by precise cell-specific changes in the expression of the genes encoding the BMP family.

In ovarian conditional mouse knockout of SMAD4, the granulosa cells undergo premature luteinization and express lower levels of follicle-stimulating hormone receptors (FSHR) and higher levels of luteinizing hormone receptors (LHR).

In addition, there is evidence that gonadotrophin surge-attenuating factor produced by small follicles during the first half of the follicle phase also exerts a negative feedback on pulsatile luteinizing hormone (LH) secretion amplitude, thus allowing a more favorable environment for follicle growth and preventing premature luteinization.