In the 1940's he joined Arthur D. Little, an industrial research company, where his specialty was low-temperature refrigeration.

R-407F is for use in medium- and low-temperature refrigeration applications (supermarkets, cold storage, and process refrigeration); direct expansion system design only.

In 1892, an order from the Guinness brewery in Dublin for a Carbon Dioxide liquefaction plant drove Linde's research into the area of low-temperature refrigeration, and in 1894 he started work on a process for the liquefaction of air.