It acts to fold the skin of the hypothenar eminence transversally.

Some parallels can be drawn with these muscles and those of the hypothenar eminence serving the little finger.

The muscles of hypothenar eminence are from lateral to medial:

The ulnar nerve is exclusively responsible for the innervations of the hypothenar eminence.

Palmar erythema is reddening of the palms at the thenar and hypothenar eminences.

They drain into a venous plexus which is situated over the thenar and hypothenar eminences and across the front of the wrist.

Three intrinsic muscles comprising a group called the hypothenar eminence, and one extrinsic, the extensor digiti minimi:

It forms the ulnar border of the palm and its spindle-like shape defines the hypothenar eminence of the palm together with the skin, connective tissue, and fat surrounding it.

This usually occurs in areas where connective tissue is thick (joints, tympanic membrane) or close to the surface of the skin (thenar and hypothenar eminences and the sides of the fingers).

In medicine, split hand syndrome is a neurological syndrome in which the hand muscles on the side of the thumb (lateral, thenar eminence) appear wasted, whereas the muscles on the side of the little finger (medial, hypothenar eminence) are spared.