In the life cycle of Elysia chlorotica, cleavage is holoblastic and spiral.

Surprisingly, both syncitial and holoblastic cleavage are present, even in closely related taxa.

The cleavage is holoblastic spiral cleavage as in other gastropods.

These holoblastic cleavage planes pass all the way through isolecithal zygotes during the process of cytokinesis.

Depending mostly on the amount of yolk in the egg, the cleavage can be holoblastic (total) or meroblastic (partial).

Early cleavage is holoblastic (total), allowing the fates of individual early cells to be explored through experimental manipulation.

Cleavage is holoblastic and rotational.

This phenomenon led to some confusion in 19 thcentury literature concerning whether garpike cleavage is holoblastic or meroblastic.

Early divisions of the egg are holoblastic (the cells divide completely) and radial (they gradually form a stack of circles).

This means that the eggs cleave completely (holoblastic); and each cleavage plane is at an oblique angle to the animal-vegetal axis of the egg.

In holoblastic eggs the first cleavage always occurs along the vegetal-animal axis of the egg, and the second cleavage is perpendicular to the first.

Amia cleavage is clearly holoblastic, producing about a dozen large yolky macromeres, upon which the smaller cells of the blastoderm rest [ 14].

In bilateral holoblastic cleavage, the divisions of the blastomeres are complete and separate; compared with bilateral meroblastic cleavage, in which the blastomeres stay partially connected.

Blastoconidium is a holoblastic conidium that is produced singly or in chains, and detached at maturity leaving a bud scar, as in the budding of a yeast cell.

Holoblastic cleavage occurs in animals with little yolk in their eggs, such as humans and other mammals who receive nourishment as embryos from the mother, via the placenta or milk, such as might be secreted from a marsupium.

In the absence of a large concentration of yolk, four major cleavage types can be observed in isolecithal cells: radial holoblastic, spiral holoblastic, bilateral holoblastic, and rotational holoblastic cleavage.