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Together, the papillary muscles and the chordae tendineae are known as the subvalvular apparatus.
The chordae tendineae are attached to papillary muscles that cause tension to better hold the valve.
They are anchored to the wall of the ventricle by chordae tendineae, which prevent the valve from inverting.
The inelastic chordae tendineae are attached at one end to the papillary muscles and the other to the valve cusps.
The distinctive valvular abnormality seen with fenfluramine is a thickening of the leaflet and chordae tendineae.
These valves do not have chordae tendineae, and are more similar to valves in veins than atrioventricular valves.
Chronic rheumatic heart disease mostly affects the mitral valve, which can become thickened with calcification of the leaflets, often causing fusion of the commissures and chordae tendineae.
In acute mitral regurgitation secondary to a mechanical defect in the heart (i.e. rupture of a papillary muscle or chordae tendineae), the treatment of choice is mitral valve surgery.