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The dopaminergic pathways are considered to be strong reward centers.
Studies suggest that novelty seeking is associated with dopaminergic pathways.
There are eight dopaminergic pathways, but the four major ones are:
The main systems at work here involve the mesolimbic and mesocortical dopaminergic pathways.
Differentiation of the midbrain dopaminergic pathways during mouse development.
Many of these interconnections are via dopaminergic pathways.
The neurons of the dopaminergic pathways have axons which run the entire length of the pathway.
It is suggested that the activation of dopaminergic pathways are what contribute to the arousal component of romantic love.
The mesolimbic pathway is one of the dopaminergic pathways in the brain that modulates behavioral responses to rewarding stimuli.
Low libido, sexual dysfunction and impotence due to blockage of the pleasure center (dopaminergic pathways)
Greater activation of dopaminergic pathways dopamine production in the striatum is associated with a higher rate of spontaneous eye blinking.
A single dose of diazepam modulates the dopamine system in similar ways to how morphine and alcohol modulate the dopaminergic pathways.
Dopaminergic pathways are neural pathways in the brain which transmit the neurotransmitter dopamine from one region of the brain to another.
The evidence of the involvement of mesolimbic and mesocortical dopaminergic pathways suggests that dreaming occurs when a motivational component is activated.
Importantly, evidence suggests that one or more lesions in striatal dopaminergic pathways may be central to the neurological deficits, especially the choreoathetoid dyskinesia and self-mutilation.
Dopaminergic pathways have been specifically correlated with the extraversion trait of the Five Factor Model of Personality.
Thus far evidence supports a process whereby cholinergic activation from the brain stem during REM activates the motivational system of the mesolimbic and mesocortical dopaminergic pathways.
Midbrain dopaminergic neurons play a critical role in multiple brain functions, and abnormal signaling through dopaminergic pathways has been implicated in several major neurologic and psychiatric disorders.
The physiological mechanism for BAS is not known as well as BIS, but is believed to be related to catecholaminergic and dopaminergic pathways in the brain.
Depression has been associated with impaired neurotransmission of serotonergic, noradrenergic, and dopaminergic pathways, although most pharmacologic treatment strategies directly enhance only 5HT and NE neurotransmission.
In Parkinsonism, there is imbalance between levels of acetylcholine and dopamine in the brain, involving both increased levels of acetylcholine and degeneration of dopaminergic pathways (nigrostriatal pathway).
Current research focuses on the dopaminergic pathways as the substrate of brain stimulation reinforcement; however, both noradrenergic and dopaminergic pathways are important in brain stimulation reinforcement.
MT receptors are expressed in many regions of the central nervous system (CNS): suprachiasmatic nucleus of the hypothalamus (SCN), hippocampus, substantia nigra, cerebellum, central dopaminergic pathways, ventral tegmental area and nucleus accumbens.
A number of studies utilizing a variety of methods such as histological, structural imaging, functional imaging, and receptor binding have supplied converging evidence that the frontal lobes and frontal-striatal dopaminergic pathways are especially affected by age-related processes resulting in memory changes.
A number of analogs of sibutramine are known that behave as SNDRIs, changing the aromatic substituent in venlafaxine can also affect the degree of noradrenergic activation, although it is unclear to what extent the dopaminergic pathways can also be affected.