degranulation

Degranulation of mast cells contributing to lung damage has also been observed.

In biochemical research, compound 48/80 is used to promote mast cell degranulation.

It stimulates mast cell degranulation, thus triggering an immune response.

This inhibited mast cell degranulation and thus reduced allergic reaction.

If the degranulation is widespread, it can cause a shock-like syndrome similar to that of an allergic reaction.

Leukocyte granules are released in response to immunological stimuli during a process known as degranulation.

The damage to the gastrointestinal tract wall is caused by eosinophilic infiltration and degranulation.

Non-immunologic mechanisms involved substances that directly cause the degranulation of mast cells and basophils.

After degranulation a CD63 marker (labeld antibodys) is added to the test tube.

It inhibits the degranulation of mast cells.

Once activated, eosinophils can begin the process of degranulation, releasing their toxic proteins in the fight against the foreign parasite.

The degranulation releases toxins that cause endothelial injury.

Furthermore, this compound also affected the degranulation reaction (IC50, 4.1 mM).

Activated neutrophils adhere to endothelial cells where degranulation occurs.

By adding EDTA to the test tube, the degranulation process is stopped immediately.

Upon degranulation, perforin inserts itself into the target cell's plasma membrane, forming a pore.

Neutrophils also release an assortment of proteins in three types of granules by a process called degranulation.

At low concentrations, MCD peptide can stimulate mast cell degranulation.

CERK has also been found to participate in the calcium-dependent degranulation of mast cells.

Recent studies in 2008 suggest that OPN also induces mast cell degranulation.

ECP is released during degranulation of eosinophils.

Studies with LYK deficient mice have shown that degranulation is still inducible.

Several antagonistic drugs are used to block the action of allergic mediators, or to prevent activation of cells and degranulation processes.

It is caused by the release (degranulation) of substances from mast cells or basophils under the influence of anaphylatoxins.

Basophils contain many granules inside the cell, which are filled with a variety of active substance triggering an allergic response upon degranulation.