Several colony stimulating factors are being tested for use against cancer.

Colony stimulating factors were first discovered in the mid-1960's.

Analysts estimate that by 1995 these companies could split a $1.5 billion market for colony stimulating factors.

One of the first goals is to use colony stimulating factors in cancer patients undergoing chemotherapy.

Colony stimulating factors may help patients tolerate higher doses of chemotherapy.

Leukine is the second drug in the family of colony stimulating factors to be approved.

Researchers are also trying to take advantage of the side effects of colony stimulating factors.

"With colony stimulating factors and their potential for changing the way cancer is treated, we're just scratching the surface."

For instance, they generate colony stimulating factors, which have a significant effect on hematopoiesis.

Colony stimulating factors also appear to increase the effectiveness of other drugs, at least in laboratory experiments.

It is a receptor for a cytokine called colony stimulating factor 1.

Colony stimulating factor 1 receptor has been shown to interact with:

Scientists believe infusions of colony stimulating factors might help patients survive while their marrow recovers.

Colony stimulating factors are so named because they were first discovered through their ability to stimulate growth of colonies of certain cells in the laboratory.

The study was paid for by Amgen, which makes a widely used colony stimulating factor, Neupogen.

Other monokines include alpha and beta interferon, and colony stimulating factors.

The effect of recombinant human granulocyte-macrophage colony stimulating factor on chemotherapy-induced myelosuppression.

Treatment is supportive with the use of antibiotics, blood products, colony stimulating factors, and stem cell transplant as clinically indicated.

Clinical trials suggest that colony stimulating factors can help cancer patients recover more quickly from chemotherapy or bone marrow transplants.

Studies of Interleukins There are roughly a half-dozen different colony stimulating factors in various stages of research.

One that seems particularly significant is granuocyte colony stimulating factor, important in promoting the growth of the white blood cells that defend against bacterial infection.

The hormone, one of a class of drugs known as colony stimulating factors, stimulates the body's production of white blood cells, a natural immune-system defense.

There are known to be 3 interferons in the body, 10 interleukins and 3 colony stimulating factors, all of which interact in various ways.

Other companies are trying to develop yet another member of the class known as M-CSF, or macrophage colony stimulating factor.

This differentiation requires stimulation by colony stimulating factor (CSF)-1.

The name "colony-stimulating factors" comes from the method by which they were discovered.

Colony-stimulating factors signal for increased transport of vitamin C in human host defense cells.

Colony-stimulating factors are sometimes given together with chemotherapy.

Analysts said that the colony-stimulating factors could also represent the most lucrative drugs yet produced by genetic engineering.

Plasmapheresis and administration of granulocyte colony-stimulating factor were used to treat the blood disorders.

It is a colony-stimulating factor that stimulates megakaryocyte production.

The scientists used a genetically engineered version of granulocyte-macrophage colony-stimulating factor, a natural hormone.

One notable example is the granulocyte macrophage colony-stimulating factor.

Human granulocyte macrophage colony-stimulating factor is glycosylated in its mature form.

It can be induced by macrophage colony-stimulating factor.

Colony-stimulating factor stimulates white blood cells and may be used to treat patients suffering from cancer, burns and diabetes.

Macrophage colony-stimulating factor has been shown to interact with PIK3R2.

Lenograstim is a recombinant granulocyte colony-stimulating factor which functions as an immunostimulator.

The gene for human granulocyte colony-stimulating factor is inserted into the genetic material of Escherichia coli.

Metcalf D. The colony-stimulating factors and cancer.

The colony-stimulating factors are soluble, in contrast to other, membrane-bound substances of the hematopoietic microenvironment.

The α subunit contains a binding site for granulocyte macrophage colony-stimulating factor.

Medical experts say the colony-stimulating factors will also probably prove useful in preventing infections in patients suffering from burns or undergoing surgery.

Granulocyte-macrophage colony-stimulating factor in combination with pentavalent antimony for the treatment of visceral leishmaniasis.

A clinical trial of combination chemotherapy and granulocyte colony-stimulating factor (substance that helps the body increase the number of white blood cells).

Finally, granulocyte-macrophage colony-stimulating factor, a very common therapy used to increase the production of white blood cells, may also cause fever, nausea, vomiting, and diarrhea.

Colony-stimulating factor derivatives.

Colony-stimulating factors include:

Sometimes granulocyte colony-stimulating factor (G-CSF) is given with erythropoietin to help the treatment work better.

This drug is a growth factor known as GCSF (granulocyte colony-stimulating factor).