This change initiates a cascade in which newly converted molecules change the shape of other normal PrP molecules, and so on.

It is suggested that the conformational change in structure triggers ATP hydrolysis and so initiates peptide transport.

From the 15th century, changes to the areas surrounding Santa María de Óvila initiated a slow decline.

The saturated sediment may appear quite solid until a sudden change in pressure or shock initiates liquefaction.

Allergies, sleeping late or napping, marked changes in the weather or atmospheric pressure, dazzling light, smoking cigarettes and hunger or fasting can also initiate attacks.

She decided to make a return visit to Scarborough in the hope that the change of location and fresh sea air might initiate a recovery.

That small change initiated a major revision of the story, and sank Danny Mills all the deeper into his alcoholic gloom.

If these losses are large enough to prompt further portfolio changes, a small change could initiate a chain reaction of losses.

This sudden change in pressure initiates the chemical (or sometimes, as in steam explosions, physical) energy release.

Any changes in the regeneration program might have initiated a sequence that was unique to the alcove.