Alviva has a large library of drugs that are potentially antiapoptotic.

Many cancer cells will overexpress antiapoptotic factors as part of tumor development.

Glyceraldehyde-3-phosphate dehydrogenase as a target for antiapoptotic drugs.

Antiapoptotic proteins, such as clusterin and survivin, are often expressed in cancer cells.

NRC researchers are working to develop drugs that are potentially antiapoptotic.

MuriGen will continue to focus on its other programs, including the development of a novel class of antiapoptotic compounds."

Activation of PP1 is crucial for ceramide antiapoptotic action.

Surprisingly, novel mitogenic, cytoprotective, and antiapoptotic activities were detected.

Bcl-2 is an antiapoptotic protein.

Her research interests include the study of poxvirus immune evasion strategies with a particular interest in viral antiapoptotic mechanisms.

ADAM15 also has an antiapoptotic effect in osteoarthritic chondrocytes.

Resveratrol acts to inhibit and decrease expression of antiapoptotic Bcl-2 family members while also increasing p53 expression.

Both proapoptotic and antiapoptotic members of this family are found in mammalian cells, but no such proteins have been described in insects.

N-Desmethylselegiline may have neuroprotective antiapoptotic properties.

Survivin is a member of the IAP family of antiapoptotic proteins.

E1B-19k mimics MCL1, which is a cellular antiapoptotic protein.

Though uncoupling the membrane potential typically leads to apoptosis, ANT2 was found to be antiapoptotic.

As a result, this protein plays an antiapoptotic role against oxidative stress, ionizing radiation, and inflammatory cytokines.

Baculovirus-based genetic screen for antiapoptotic genes identifies a novel IAP.

Scientists recognise activated protein C's antiapoptotic effects, but are unclear as to the exact mechanisms by which apoptosis is inhibited.

This is likely to be due to its activation of the NF-κB pathway, which is antiapoptotic.

Its glycolytic and antiapoptotic functions contribute to proliferation and protection of tumor cells, promoting tumorigenesis.

Further preclinical research needs to be performed to clearly establish this therapeutic approach that could be optimized by the early administration of antiapoptotic cytokines.

This observation suggests that the antiapoptotic MUL1 serves as a tumor suppressor and is thus downregulated in cancer cells.

Because its activity is suppressed in the presence of survival-promoting proteins, this protein is suggested as a likely target for antiapoptotic proteins.

It appears that other factors influence the anti-apoptotic activity of antioxidants.

A rather surprising property of Daxx is its anti-apoptotic function.

Another gene has been discovered to have anti-apoptotic properties.

They have been implicated, however, to play a role in maintaining an anti-apoptotic environment intracellularly.

This protein promotes apoptosis through an interaction with anti-apoptotic members of the Bcl-2 family.

When anti-apoptotic family members are overexpressed, apoptotic cell death becomes less likely.

However, the potential anti-apoptotic mechanisms present early in the course were ineffective by day 21, when caspase-8 activation was evident.

The over-expression of the anti-apoptotic Bcl-2 protein in lymphocytes alone does not cause cancer.

MDC1 can execute its anti-apoptotic activity by inhibiting p53 in two ways.

PD1 has a significant role as an anti-inflammatory, anti-apoptotic and neuroprotective molecule.

There are a number of theories concerning how the Bcl-2 gene family exert their pro- or anti-apoptotic effect.

It may regulate apoptosis via regulation of p53-dependent anti-apoptotic genes.

Bcl-2 is the most well known of the anti-apoptotic members, and is classified as an oncogene.

Cell-surface receptors that might promote anti-apoptotic activity must be identified as well.

B-cell lymphoma-2 (Bcl-2) family members create a balance between pro and anti-apoptotic proteins.

Anti-apoptotic genes could, in principle, be incorporated into therapies.

Bcl-2 (on chromosome 18), which gives the fusion protein anti-apoptotic abilities.

ABCB5 was further shown to be anti-apoptotic in these adult stem cells.

H2S is a cardioprotective agent that has antioxidant, anti-inflammatory, and anti-apoptotic effects,.

OPN is an important anti-apoptotic factor in many circumstances.

Bcl-2 is specifically considered an important anti-apoptotic protein and is thus classified as an oncogene.

Purine-derivatives typically have neurotrophic effects, some of which appear relevant to anti-apoptotic processes.

This gene encodes a pro-survival (anti-apoptotic) member of the bcl-2 protein family.

Renalase is secreted in plasma, and functions as an anti-apoptotic survival factor.

Moreover, these cells exhibited decreased apoptosis and expressed the anti-apoptotic protein, Mcl-1.