Five minutes would have made a lot of difference to me.

A few minutes would have made no difference to them.

Even a few minutes a day can make a difference.

A few minutes more, and nothing would make any difference to anything ever again.

And a few minutes more won't make that much difference.

In Security, one minute can make the difference between life and death.

A few more minutes either way wouldn't make that much of a difference to anyone.

A minute or two earlier would have made all the difference.

A few minutes one way or the other won't make that much difference.

"I didn't think a few minutes could make that much of a difference."