During the 1950s and 1960s, South Midland ran coaches between Oxford and London about every hour, alternating between the High Wycombe and Henley routes.

Loudwater was once served by the High Wycombe to Bourne End railway line, the station being situated at the bottom of Treadaway Hill.

Flackwell Heath FC was formed in 1907, joining the High Wycombe and District League for its inaugural season.

Towns such as High Wycombe in Buckinghamshire are earmarked as temporary care shelters for evacuees.

From 1940 to 1968 High Wycombe was the seat of the RAF Bomber Command.

The High Wycombe Amateur Boxing Club is located on Leigh Street.

In 1877 High Wycombe, famous for its chair manufacturing, built a chair arch for the visit of Queen Victoria to Disraeli at his home, Hughenden Manor.

Also the M40 runs through or skirts major connurbations, such as High Wycombe, where there is not the space to build a railway alongside the motorway (at least in some parts).

The village was once served by the High Wycombe to Bourne End railway line, however the line and station closed in 1970.

The High Wycombe urban area (with some surrounding settlements) population is 118,229.