In the spinal cord is found the anterior white commissure.

Two of the five sensory modalities, pain and temperature, cross sides at the anterior white commissure.

Their axons cross in the anterior white commissure.

(b) fibers which cross in the anterior white commissure from the gray substance of the opposite side.

These second order fibers then cross the cord via the anterior white commissure and ascend in the spinothalamic tract.

Most of them will cross to the contralateral side of the cord (via the anterior white commissure) right before synapsing.

These fibers cross through the anterior white commissure to form the Anterior lateral system in the lateral funiculus.

The axons of these neurons cross the midline (decussate) through the anterior white commissure and ascend contralaterally along the anterolateral columns.

The tectospinal, vestibulospinal and reticulospinal descend ipsilaterally in the anterior column but do not synapse across the anterior white commissure.

This typically damages white matter fibers that cross in anterior white commissure, leading to the loss of temperature, pain, and motor function at the affected levels on contralateral sides.

The netrins act as chemoattractants to decussation of pain and temperature sensory neurons in the alar plate across the anterior white commissure, where they then ascend towards the thalamus.

Most of these fibers cross over to the contralateral lateral funiculus via the anterior white commissure and proceed up the spinal cord to synapse with neurons in the superior cerebellar peduncle.

The gray commissure is a thin strip of gray matter that surrounds the central canal of the spinal cord and, along with the anterior white commissure, connects the two halves of the cord.

The axons of the tract cells cross over (decussate) to the other side of the spinal cord via the anterior white commissure, and to the anterolateral corner of the spinal cord (hence the spinothalamic tract being part of the anterolateral system).

It contains a double fold of pia mater, and its floor is formed by a transverse band of white substance, the anterior white commissure, which is perforated by blood vessels on their way to or from the central part of the medulla spinalis.

Impulses are then transmitted to nerve fibers that terminate in lamina V, also in the dorsal horn, synapsing with neurons that join fibers from the fast pathway, crossing to the opposite side via the anterior white commissure, and traveling upwards through the anterolateral pathway.