Common variable immunodeficiency is thought to be due to a problem in the differentiation from lymphocytes to plasma cells.

Common variable immunodeficiency is the most commonly encountered primary immunodeficiency.

BLyS itself could be a useful treatment for a group of disorders known as common variable immunodeficiency.

Hypogammaglobulinemia is a characteristic of common variable immunodeficiency.

Antibody deficiencies are also common, including common variable immunodeficiency and IgA deficiency.

Although it has some similarities to common variable immunodeficiency, it does not present the same lymphocyte subpopulation abnormalities.

It is thought that Common Variable Immunodeficiency may result from a combination of genetic defects or from different disease genes (heterogenous).

Other causes include inherited immunodeficiency conditions, such as combined variable immunodeficiency, IgA deficiency, and hypogammaglobulinemia.

Certain other immune deficiency states (e.g. common variable immunodeficiency and IgA deficiency) are also associated with increased risk of malignancy.

Common variable immunodeficiency (CVID)

Aghamohammadi A, Parvaneh N, Tirgari F, et al.: Lymphoma of mucosa-associated lymphoid tissue in common variable immunodeficiency.

Other immune problems range from severe immune deficiencies of childhood such as Wiskott-Aldrich syndrome to less severe deficiencies such as common variable immunodeficiency.

In some cases, individuals with Common Variable Immunodeficiency have an increased tendency to develop certain diseases characterized by abnormal tissue growths (neoplasms) that may be benign or malignant.

A variety of immune deficiencies present at birth such as ataxia-telangectasia, Wiskott-Aldrich syndrome, common variable immunodeficiency, severe combined immunodeficiency, and X-linked lymphoproliferative syndrome.

"Clinical and immunological features of 65 Iranian patients with common variable immunodeficiency " Clinical and Diagnostic Laboratory Immunology 12 (7), pp.

One example is common variable immunodeficiency (CVID) where multiple autoimmune diseases are seen, e.g. inflammatory bowel disease, autoimmune thrombocytopenia and autoimmune thyroid disease.

The term "Common Variable Immunodeficiency" is used to designate an immune defect in which there is a substantial reduction of the level of immunizing agents (immunoglobulins) in the fluid portion of the blood (serum).

Common variable immunodeficiency (CVID): B-cell levels are normal in circulation but with decreased production of IgG throughout the years, so it is the only primary immune disorder that presents onset in the late teens years.