tolbutamide

Hypoglycemia, or low blood sugar, is the most common side effect of tolbutamide.

Other diabetes medicines are sometimes used in combination with tolbutamide if needed.

Stop taking tolbutamide and call your doctor at once if you have a serious side effect such as:

Searching through the medicine cabinet, she found a container labelled Tolbutamide.

Follow your doctor's instructions about how often to take tolbutamide, and whether or not you should take it with food.

Ask your doctor how to adjust your tolbutamide dose if needed.

A number of different routes are available for the preparation of tolbutamide.

Your pharmacist can provide more information about tolbutamide.

Talk to your doctor about the risks and benefits of treating your diabetes with tolbutamide.

You should not breast-feed while you are taking tolbutamide.

A case can be made for giving tolbutamide to those 65 years and over who are obese Type 2 patients and need an oral agent.

To make sure you can safely take tolbutamide, tell your doctor if you have any of these other conditions:

Don't drink beer if you are taking tolbutamide (Orinase).

The heritage of Orinase (tolbutamide) has had a lasting effect on medicine and the pharmaceutical industry.

It is not known whether tolbutamide passes into breast milk or if it could be harmful to a nursing baby.

Your blood sugar will need to be checked often, and you may need to adjust your tolbutamide dose.

An overdose of tolbutamide can cause severe hypoglycemia.

These lists are not complete and there are many other medicines that can increase or decrease the effects of tolbutamide on lowering your blood sugar.

FDA pregnancy category C. It is not known whether tolbutamide will harm an unborn baby.

It can cause relatively long episodes of hypoglycemia; this is one reason why shorter-acting sulfonylureas such as gliclazide or tolbutamide are used instead.

Drinking wine and taking tolbutamide (Orinase) can cause pounding headache, vomiting, flushing, and other unpleasant reactions.

Clearly a short-acting sulphonylurea such as tolbutamide or a medium-acting one such as glibenclamide is particularly useful in this situation.

You may be more likely to have hypoglycemia (low blood sugar) if you take tolbutamide with other drugs that can lower blood sugar, such as:

Due to varying half-life, some drugs have to be taken two (e.g. tolbutamide) or three times a day rather than once (e.g. glimepiride).

With the introduction of sulphonylureas in the 1950s it was found that tolbutamide could improve or normalize carbohydrate tolerance in some young non-obese mildly diabetic patients.