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Information about the light/dark cycle is transmitted from the retina to the paired suprachiasmatic nuclei in the hypothalamus.
In mammals, such endogenous rhythms are generated by the suprachiasmatic nuclei of the anterior hypothalamus.
The suprachiasmatic nuclei receive and interpret information on environmental light, dark and day length, important in the entrainment of the "body clock".
The neurons within the suprachiasmatic nuclei region of the brain help to regulate REM sleep.
From more complex eyes, retinal photosensitive ganglion cells send signals along the retinohypothalamic tract to the suprachiasmatic nuclei to effect circadian adjustment.
In 1993, Takahashi and Michael Greenberg studied the mechanisms of mammalian suprachiasmatic nuclei entrainment to environmental light cycles.
One particular component, the suprachiasmatic nuclei, is responsible for the circadian (or daily) rhythm, while other cell clusters appear capable of shorter-range (ultradian) timekeeping.
Rubidium chloride has been shown to modify coupling between circadian oscillators via reduced photaic input to the suprachiasmatic nuclei.
The MT subtype is present in the pars tuberalis of the pituitary gland and the suprachiasmatic nuclei of the hypothalamus.
VIP is produced in many tissues of vertebrates including the gut, pancreas and suprachiasmatic nuclei of the hypothalamus in the brain.
Interest has centred on the role of two small groups of cells, one on either side of the brain, that are called the suprachiasmatic nuclei (SCN).
More-or-less independent circadian rhythms are found in many organs and cells in the body outside the suprachiasmatic nuclei (SCN), the "master clock".
One region of the brain includes a specific area of the suprachiasmatic nuclei (SCN), the location of the 'master circadian pacemaker'.
The raphe nuclei provide feedback to the suprachiasmatic nuclei (SCN), thus contributing in circadian rhythms in animals.
Its main function, secretion of the hormone melatonin, dies out when there is no input from the primary circadian pacemaker in the suprachiasmatic nuclei (SCN).
The axons of the ipRGCs belonging to the retinohypothalamic tract project directly, monosynaptically, to the suprachiasmatic nuclei via the optic nerve and the optic chiasm.
The part of the brain that is thought to be a key component of the body's clock, the suprachiasmatic nuclei, "is heavily endowed with nerve cells rich in serotonin," he explained.
In mammals, this process is driven by the suprachiasmatic nuclei (SCN) in the hypothalamus, composed of the two negative feedback loops Per-Cry and Clock-Bmal.
In the cortex, the suprachiasmatic nuclei have been shown to regulate delta waves, as lesions to this area have been shown to cause disruptions in delta wave activity.
Their information is sent to the SCN (suprachiasmatic nuclei), not to the visual center, through the retinohypothalamic tract which is formed as melanopsin-sensitive axons exit the optic nerve.
In humans and other mammals, the light signals necessary to set circadian rhythms are sent from the eye through the retinohypothalamic system to the suprachiasmatic nuclei (SCN) and the pineal gland.
The hypothalamic internal "master" clock in the suprachiasmatic nuclei had recently been discovered, with a primary function of programming daily cycles of physiology and behavior even in the absence of day-night cues.
GRP is also involved in the biology of the circadian system, playing a role in the signaling of light to the master circadian oscillator in the suprachiasmatic nuclei of the hypothalamus.
Evidence supporting prior theories that melanopsin is the photopigment responsible for the entrainment of the central "body clock", the suprachiasmatic nuclei (SCN), in mammals was provided by King-Wai Yau and colleagues at Princeton.
Vasoactive intestinal peptide (VIP, also polypeptide) is a kind of hormone that has 28 amino acid residues in it and is made in many areas of the human body including the gut, pancreas, and suprachiasmatic nuclei (which is a small part of the brain's midline) of the hypothalamus in the brain.